Job Description

Associate Scientist, Engineered Cell Therapy Discovery Join to apply for the Associate Scientist, Engineered Cell Therapy Discovery role at Bristol Myers Squibb . Overview Working with Us: Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us. The Cell Therapy Thematic Research Center focuses on developing and translating engineered cell-based therapies for cancer and autoimmune diseases. Our discovery and translational science teams aim to advance next-generation cellular therapies that harness the power of the immune system to improve patient outcomes. Position Summary The Engineered Cell Therapy Discovery team has an opening for a highly motivated Associate Scientist dedicated to discovery and development of novel engineered CAR T and eTCR T cell therapeutics for the treatment of cancer and other chronic diseases. The successful candidate will contribute to conceptual design and functional testing of advanced circuits engineered into CAR T cells and generate robust, reproducible datasets to drive immune cell engineering projects. This role interfaces with senior researchers to execute studies, analyze data and communicate results. This position is ideal for an innovative scientist who leads with data to drive decisions for drug discovery. Position Responsibilities Contributes to the development of in vitro assays for target validation and functional modulation of novel targets Designs and develops complex in vitro models to study mechanism of action and pharmacology of engineered T cells Working knowledge of bioinformatics with the ability to analyze and interpret transcriptomic/proteomic data for target identification Supports the conceptual design and functional testing of CARs and/or advanced logic circuits engineered into CAR T cells. Participates in go/no-go decision-making processes to drive development of cutting-edge cell therapies. Develops and optimizes novel assays to quantitatively assess the biological and functional properties of CARs and novel circuits built into engineered T cells. Ensures robustness and reproducibility of these assays to support key project milestones. Generation, expansion, characterization, and cryopreservation of CAR T cells and eTCR T cells. Performs phenotypic and functional analysis of CAR T cells using flow cytometry, IncuCyte, and other relevant methods. Analyzes data to provide insights into performance, quality, and potential of engineered T cells. Active participation in troubleshooting and continuous improvement initiatives related to new approaches/technologies. Collaborates effectively with cross-functional teams. Communicates findings clearly to stakeholders at all levels. Maintains electronic notebooks to support project milestones and regulatory filings. Qualifications Basic Qualifications Bachelor's Degree 2+ years of industry and/or academic experience Preferred Qualifications Bachelor's Degree and 2+ years of industry experience Strong quantitative and analytical abilities to provide insights into engineered T cell performance Excellent organizational skills for thorough documentation of experiments across multiple projects. Maintains electronic notebooks rigorously. Ability to independently recognize potential problems and recommend/develop appropriate solutions Strong communication skills for working with cross-functional teams Experience developing and using quantitative in vitro assays to drive decision-making, especially in drug development Proficient in MSD, IncuCyte-based assays, multi-parameter flow cytometry, T cell activation assays, and T cell proliferation analysis Experience with molecular biology, protein function/folding, cell signaling, high throughput screening, automation, CRISPR gene editing, and/or imaging technologies Skilled in generating, expanding, characterizing, and cryopreserving CAR T and eTCR T cells Ability to work productively as both a team member and an individual contributor Developed knowledge of principles and concepts of biological sciences, immunology, bioengineering, or related discipline Compensation Overview Seattle - WA: $92,900 - $112,569. The starting compensation range is listed for a full-time employee (FTE). Additional incentive cash and stock opportunities (based on eligibility) may be available. Final, individual compensation will be decided based on demonstrated experience. Eligibility for benefits listed on our careers site may vary by job and location. For more on benefits, please visit Benefit offerings include medical, dental, vision, wellbeing resources and programs, 401(K), disability and life insurance, paid holidays and time off, and other programs. Uniquely Interesting Work, Life-changing Careers With a single vision as inspiring as Transforming patients' lives through science, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our talents and perspectives in a supportive culture, promoting global participation in clinical trials while upholding our values of passion, innovation, urgency, accountability, inclusion and integrity. On-site Protocol BMS has an occupancy structure that determines where an employee is required to conduct their work. The occupancy type is determined by the responsibilities of your role: site-essential (100% onsite), site-by-design (hybrid with at least 50% onsite), or field-based/remote-by-design (travel as needed). BMS is committed to accessibility and reasonable accommodations. If you require accommodations, contact adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility for our Equal Employment Opportunity statement. BMS cares about well-being and recommends vaccination for Covid-19 and staying up to date with boosters. BMS will consider applicants with arrest and conviction records, per applicable laws. If you live in Los Angeles County, see for more information. Data collected in role applications is treated in accordance with our privacy policies. Seniority level Entry level Employment type Full-time Job function Research, Analyst, and Information Technology Industries: Pharmaceutical Manufacturing Data and postings are subject to change. This posting may include additional information not reflected in this refined description. #J-18808-Ljbffr Bristol Myers Squibb

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